New pre-print posted to bioRxiv! Jack, in collaboration with the Moremen (CCRC) and Liu (UNC) labs, performed CRISPR activation screens to reveal that core proteoglycan proteins regulate heparan sulfate sulfation and ligand binding!

Excited to share our latest preprint on bioRxiv! Neil and collaborators report how EZH2 drives melanoma metastasis through a non-canonical epigenetic pathway that remodels heparan sulfate at the tumor cell surface!

New pre-print now available on bioRxiv! Xiaolin led a study reporting a previously unrecognized role for mucin-type O-glycans in maintaining proteoglycan stability and signaling, with implications for skeletal development and glycosylation-related disorders.!

Amrita and Dr. Weiss contributed to an exciting study now published in Nature! GAGs play a key role in promoting lipoprotein uptake to protect tumors from ferroptosis.